Author

Qing-Feng Liang

3 papers indexed here

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Open access Sep 2026

A Novel Mycovirus Reprograms the Pathogenic State of Aspergillus flavus in Keratitis

Purpose Fungal keratitis (FK) is a major cause of corneal blindness, with substantial variability in disease severity that cannot be fully explained by host factors. This study investigated whether endogenous mycovirus infection contributes to differences in fungal pathogenicity. Methods Fungal isolates from 38 patient...

Zhen Cheng, Xin Luo, Qing-Quan Shi et al. · Investigative Ophthalmology... · 0 citations

Open access Oct 2026

Temporal Transcriptomic Profiling Reveals DECTIN-1–Mediated Immune Responses in Acanthamoeba Keratitis

Purpose The purpose of this study was to investigate the dynamic immune response and the role of DECTIN-1 in Acanthamoeba keratitis (AK). Methods The AK mouse model was established, and corneal tissue samples were collected at 1, 3, and 7 days post-infection (dpi). Transcriptomic profiling was performed to analyze diff...

J. Pang, Zhen-Yu Wei, Yu-Heng Zhang et al. · Investigative Ophthalmology... · 0 citations

Open access Sep 2026

Cross-Serotype Protection of a PstS-YidR Fusion mRNA Vaccine Against Systemic Infection and Endogenous Endophthalmitis Caused by Hypervirulent Klebsiella pneumoniae

Background: Hypervirulent Klebsiella pneumoniae (K. pneumoniae) easily causes bacteremia and liver abscess, and invades the eye via blood circulation to trigger blinding endogenous endophthalmitis. Widespread multidrug resistance limits antibiotic treatment, while traditional capsular polysaccharide vaccines cannot pro...

Jia-Ying Lei, Xin-Xin Lu, Ti-Yun Han et al. · Pathogens · 0 citations