Qing-Hui Shang

Lactate promotes mitochondrial biogenesis and fusion via GPR81 to enhance synaptic plasticity-related protein expression in hippocampal cells

Beyond its traditional role as a glycolysis end-product, lactate is now recognized as an important signaling molecule influencing synaptic plasticity and mitochondrial activity. We examined whether lactate, acting through its receptor GPR81, improves synaptic plasticity-related protein expression by augmenti...