CXCL9 drives lung adenocarcinoma progression and immunotherapy response via activation of the CXCR3/JAK1/STAT3 signaling pathway.
BACKGROUND C-X-C Motif Chemokine Ligand 9 (CXCL9) is an immune-related chemokine implicated in tumor progression and immunotherapy response. However, its biological role and regulatory mechanisms in lung adenocarcinoma (LUAD) remain unclear. METHODS Public immunotherapy cohorts, The Cancer Genome Atlas (TCGA) pan-can...