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Author

Qing-Lan Yuan

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Sep 2026

Bruceine D suppressed osteoclast formation via STAT3/NF-κB/NFATc1 signaling and protected postmenopausal osteoporosis

It is demonstrated that BD significantly inhibited RANKL-induced osteoclast differentiation in a dose-dependent manner without cytotoxic effects at effective concentrations, and protects against estrogen deficiency-induced bone loss by inhibiting the STAT3/NF-κB/NFATc1 signaling axis.

Si-Si Lin, Qing-Lan Yuan, Xin-Yi Yao et al. · 0 citations

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