Author

Qing Nie

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Open access Sep 2026

Learning stochastic dynamics and cell-fate landscapes from single-cell snapshots via optimal transport

The temporal dynamics and stochasticity of gene expression are critical to cell fate decisions, yet integrating snapshot omics data across multiple time points remains a major challenge. Here, we introduce DiffusionOT, a dynamic machine learning framework that infers cellular trajectories from multi–time point single-c...

Jun-Tan Liu, Peijie Zhou, Qing Nie et al. · Science Advances · 0 citations

Review Open access Aug 2026

Robust identification of cell-cell communication heterogeneity in single cells.

Cell-cell communication modulates cell fate decisions by relaying information across tissues and inducing intracellular responses mediated by gene regulatory networks. Although the inference of cell-cell communication from high-throughput data is gaining popularity, studying how communication pathways operate across bi...

F. Bocci, Yunlong Y. Jia, Scott Atwood et al. · Cell Systems · 0 citations