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Qing-Song Wang

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Review Open access Jul 2026

The role of OTUD1-mediated deubiquitination in disease pathogenesis: from molecular mechanisms to clinical translation

This review systematically summarizes the molecular characteristics, physiological functions, disease regulatory networks, and current clinical translational status of OTUD1 with the aim of clarifying the molecular basis of its functional duality and providing a theoretical foundation for optimizing precision diagnosti...

Qing-Song Wang, Lijuan Zhang, Hong-Mei Cao et al. · 0 citations
Review Open access Jul 2026

Targeting the deubiquitinase USP28 in cancer: navigating context-dependent mechanisms and therapeutic resistance

A review of the molecular characteristics and physiological functions of USP28, its context-dependent roles in neoplastic diseases, and its translational implications for targeted therapy and biomarker discovery highlights its potential as a therapeutic target for precision medicine.

Tong-Yong Luo, Shuncai Wu, Qing-Song Wang et al. · 1 citation
Review Open access Jul 2026

RNA-binding protein RBM47 in health and disease: molecular mechanisms, preclinical evidence, and translational challenges

The molecular characteristics and pathological mechanisms of RBM47 are summarized, the preclinical rationale for its potential utility as a biomarker and therapeutic node is discussed, and current research limitations, conflicting evidence, and translational bottlenecks are critically analyzed.

Shihua Huang, Qingsong Wang, Junhong Shen et al. · 0 citations
Review Open access Jul 2026

The RNA-binding protein CELF4: from molecular regulatory networks to clinical translation in cross-system diseases

The molecular regulatory networks of CELF4 and its mechanisms across multisystem diseases are reviewed, the current status and limitations of clinical translation are discussed, and future research on diagnostic biomarkers and therapeutic strategies targeting this protein is guided.

Qingsong Wang, Wenlong Yue, D. Lin et al. · 0 citations

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