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Sep 2026

Polymyxin B Attenuates Sepsis‐Induced Acute Kidney Injury by Activating a SUMO1‐p65 “Molecular Brake” in Kidney Organoids

A novel therapeutic paradigm is established by underscoring the promise of targeting PTM pathways to alleviate septic organ dysfunction by identifying the SUMO1-p65 axis constitutes a pivotal regulatory checkpoint for PMB-mediated immunomodulation.

Qing Wang, Na Xue, Tian Yu et al. · 0 citations

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