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Sep 2026

Wearable Microfluidic Chip Integrated with Chrono-Sampling for Cortisol Detection in Sweat

Sweat is rich in various biomarkers, including metabolites, hormones, and inorganic ions, and thus, it provides a wealth of physiological information. The real-time monitoring of these biomarkers preserves critical dynamic physiological data, enabling a more comprehensive assessment of the health status. For a sensor...

Ya-Nan Luan, Yi Huang, Ming-Ze Ma et al. · 1 citation
Sep 2026

Aptamer-Functionalized DNA Frameworks as Targeted Drug Buffers for Concentration Regulation of Maytansine.

Traditional chemotherapy often suffers from nonspecific distribution and poor drug concentration control, leading to compromised therapeutic efficacy and adverse effects. Mertansine (DM1), a potent cytotoxic agent with poor selectivity, dose-limiting toxicity, and a narrow therapeutic window, demands targeted delivery...

Dan Jiang, Jiao-Jiao Li, Ying Xiao et al. · 0 citations
Jul 2026

Multiplexed Detection of Breast Cancer-Specific miRNA and Protein Biomarkers on Exosomes Using a Microfluidic Platform.

A microfluidic chip integrating two signals (ALP-driven chemiluminescence and nanobeacons-based fluorescence) into a single device was developed using breast cancer exosomes as a model, and this five-marker biomarker panel achieved a diagnostic accuracy of 99.6% in breast cancer identification.

Hongqian Wang, Hui Liu, Ya-Nan Luan et al. · 0 citations

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