Sweat is rich in various biomarkers, including metabolites, hormones, and inorganic ions, and thus, it provides a wealth of physiological information. The real-time monitoring of these biomarkers preserves critical dynamic physiological data, enabling a more comprehensive assessment of the health status. For a sensor...
Ya-Nan Luan, Yi Huang, Ming-Ze Ma et al.· Analytical Chemistry· 1 citation
Traditional chemotherapy often suffers from nonspecific distribution and poor drug concentration control, leading to compromised therapeutic efficacy and adverse effects. Mertansine (DM1), a potent cytotoxic agent with poor selectivity, dose-limiting toxicity, and a narrow therapeutic window, demands targeted delivery...
Dan Jiang, Jiao-Jiao Li, Ying Xiao et al.· ACS Applied Bio Materials· 0 citations
A microfluidic chip integrating two signals (ALP-driven chemiluminescence and nanobeacons-based fluorescence) into a single device was developed using breast cancer exosomes as a model, and this five-marker biomarker panel achieved a diagnostic accuracy of 99.6% in breast cancer identification.