Author

Qing-wen Tao

3 papers indexed here

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Sep 2026

Association of clinical-immunologic clusters and anti-RNP/Ro52 antibody profiles with prognostic trajectories in primary Sjögren's disease.

OBJECTIVE To delineate the prognostic architecture of primary Sjögren's disease (pSjD) through an integrated analysis of clinical-immunologic clusters and anti-RNP/anti-Ro52 antibody profiles. METHODS This ambispective cohort study enrolled 1293 patients with pSjD from China-Japan Friendship Hospital (2013-2023). Uns...

Bo Tang, Yan Zhang, Xin-Bo Yu et al. · Journal of Autoimmunity · 0 citations

Open access Aug 2026

Characterization of Peripheral Blood Immune Cell Features in SSA/SSB Double‑Positive Primary Sjögren’s Disease Based on Single‑Cell RNA Sequencing

Objective Primary Sjögren’s disease (pSjD) is a chronic systemic autoimmune disease characterized by lymphocyte infiltration of the exocrine glands. Anti-SSA (Ro) and anti-SSB (La) antibodies are diagnostic serological markers of pSjD. However, whether the coexistence of anti-SSA and anti-SSB antibodies defines an immu...

Peng-Rui Wang, Fei Teng, Yifei Wang et al. · Journal of Inflammation Rese... · 1 citation

Open access Jul 2026

Single-cell expression quantitative trait loci-based Mendelian randomization identifies MAN1A2 in naive CD4+ T cells as a candidate therapeutic target for osteoarthritis.

BACKGROUND Osteoarthritis (OA) is a leading cause of chronic pain and disability worldwide, with growing evidence implicating immune dysregulation in its pathogenesis. However, the specific peripheral immune cell populations contributing causally to OA risk remain poorly characterized. METHODS We performed a multi-st...

Xuanyi Zhou, Fangyu Liu, Yan Zhang et al. · Experimental Gerontology · 0 citations