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Qing-Wen Wang

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Open access Sep 2026

SIRT1-mediated deacetylation of Lysyl-tRNA synthetase reprograms lipid metabolism to promote colorectal tumorigenesis

Aminoacyl-tRNA synthetases (AARSs) have long been recognized for their canonical role in protein synthesis, catalyzing the attachment of amino acids to their cognate tRNAs. However, accumulating evidence has revealed that many AARSs also exert non-canonical functions under various physiological and pathological con...

Chao-Qun Li, Qing-Wen Wang, Kai-Lun Liu et al. · 0 citations

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