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Review Open access Aug 2026

Microenvironmental Control of Thyroid Cancer Plasticity and Radioiodine Resistance

Functional dedifferentiation is distinguished from epithelial–mesenchymal transition, stemness, and lymph-node metastasis, and therapeutic strategies that combine tumor-cell redifferentiation with targeting of microenvironmental feedback to restore durable radioiodine sensitivity are discussed.

Qing Ye, Xiao-Ping Yu · 0 citations

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