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Author

Qing-Yun Liu

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Open access Aug 2026

Desiccation promotes DNA damage and rifampin resistance in Mycobacterium tuberculosis.

Mycobacterium tuberculosis (Mtb) is an obligate human pathogen that depends on its ability to spread from host to host to survive as a species. Knowledge of traits supporting transmission is lacking. Here, because desiccation occurs during the generation of Mtb-transmitting aerosol droplets, we exposed Mtb mounted atop...

C. Brown, Brendon M. Lee, H. M. Liu et al. · 1 citation
Open access Sep 2026

Polyketide synthase 12 is an in vivo essential source of novel mycolyl lipids in Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) is a major pathogen worldwide that infects and transmits only among humans, yet nearly all in vivo virulence research occurs in non-human hosts. To overcome this central challenge in tuberculosis research, we leveraged a dataset of more than 50,000 sequenced isolates to identify Mtb gen...

Gregory H. Babunovic, Sanne van der Niet, M. Gontijo et al. · 0 citations

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