This review critically synthesizes the cytoprotective roles, evidence boundaries, translational challenges, and future directions of Nrf2/HO-1 signaling in RNDs, organized around retinal cell types, redox homeostasis-related injury mechanisms, disease-specific evidence, and intervention strategies.
ABSTRACT Dietary polysaccharides are important bioactive components of functional foods and play a key role in modulating host metabolism through interactions with the gut microbiota. Lycium barbarum polysaccharides (LBP) are widely consumed as dietary supplements; however, their nutritional relevance in linking gut mi...
Yi-Jing Yang, Jun Peng, Danyang Li et al.· Food Science & Nutrition· 0 citations
Retinal degeneration is characterized by progressive photoreceptor loss driven by oxidative stress and chronic inflammation, yet effective mutation-independent therapeutic strategies remain limited. Lycium barbarum polysaccharides (LBPs) possess antioxidant and anti-inflammatory activities; however, the structural feat...
Yijing Yang, Shu-Ting Yin, Ying Deng et al.· Antioxidants· 0 citations
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