Review
Open access
Aug 2026
The dual role of the cGAS-STING signaling pathway in kidney diseases: from acute injury to chronic fibrosis – molecular mechanisms and precision therapeutic strategies
The cGAS-STING pathway has emerged as a central hub linking kidney injury to inflammation, metabolism, and fibrosis, and its precise modulation holds transformative therapeutic promise for hundreds of millions of patients with kidney diseases worldwide.
Guang-Dong Qi, Fei Xue, Hua-Lin Sun et al.
· Frontiers in Pharmacology · 3 citations