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Qiong-Liu Yu

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Aug 2026

Paving the way for immunotherapy: Simvastatin-primed dual-targeting NPTAC overcomes immune resistance in hepatocellular carcinoma.

A "Pave the Way Strategy" combining simvastatin (SIM) with a dual-targeted nanoparticle-mediated targeting chimera (Hs/αPD-L1-NPTAC) enables precise HCC targeting and synchronous intracellular functions and provides a promising approach to overcome ICB resistance and enable precision immunotherapy for HCC.

Chen Chen, Quanwei Sun, Qiong-Liu Yu et al. · 0 citations

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