Author

Qiu-Han Xu

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Sep 2026

Mapping Cell-Type-Specific Regulatory Variants in Vascular Dementia by Integrating Single-Cell Chromatin Accessibility and Gene Expression.

BACKGROUND Vascular dementia (VaD), the second most common form of dementia, is a growing burden in aging populations and lacks disease-modifying therapy. Although immunerelated regulatory mechanisms are increasingly implicated, the role of immune cell-specific chromatin accessibility variants remains poorly understood...

Qiu-Han Xu, Zhao-Hui Chai, Yu-Ning Zhang et al. · Current Neuropharmacology · 0 citations

Open access Jul 2026

Refining the link between REM sleep behavior disorder and neurodegeneration: Genetic correlation, Mendelian randomization, and colocalization evidence

Findings provide robust genetic evidence supporting a causal relationship between iRBD and the risk of multiple neurodegenerative diseases, highlighting the potential for shared pathophysiological mechanisms.

Hong Ye, Jia-Li Wang, Qiu-Han Xu et al. · Medicine · 0 citations