Open access
Sep 2026
Integrated Transcriptomic and Functional Analyses Identify SERPINE1 as a Ferroptosis-Associated Mediator of Glioblastoma Radioresistance.
BACKGROUND Radiotherapy failure remains a major challenge in glioblastoma (GBM), yet the stress-adaptive programs that enable tumor cells to survive irradiation-induced lethal injury remain incompletely defined. This study investigated whether serpin family E member 1 (SERPINE1) contributes to GBM radioresistance by mo...
Yu-Hang Wang, Yan-Ting Li, Meng Dong et al.
· Frontiers in Bioscience · 0 citations