Aug 2026
Captopril Enables the Inhibition of tRNA-Mediated Tau Aggregation
Using in vitro reconstitution and high-resolution imaging, tRNA is identified as a major inducer of tau aberrant aggregation and captopril effectively inhibits both general and tRNA-induced tau aggregation, positioning CAP as a potential therapeutic candidate.
Boru Peng, Quan Deng, Xiaohua Zhu et al.
· Langmuir · 0 citations