Jul 2026
In-Utero Imprinting of Gene Regulatory Networks Underpinning Innate-Like T Cell Development 2260347
Using mice carrying a mutation in the CBFβ2 isoform, it is demonstrated that CBFβ2 haploinsufficiency rewires transcriptional regulatory circuits in adult bone marrow progenitors, rendering them permissive for an early life-restricted Tγδ17 cells.
Michela Frascoli, Alyssa Berthelette, Joonsoo Kang et al.
· Journal of Immunology · 0 citations