Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a highly heterogeneous and aggressive malignancy originating from the intrahepatic bile duct epithelial cells. Despite advances in surgery, chemotherapy, targeted therapy, and immune checkpoint inhibitor (ICI)‐based regimens, durable disease control remains l...
Meng-Yao Chen, Shuo-Fan Jin, Yuxuan Zhou et al.· Clinical and Translational M...· 0 citations
This review evaluates diverse nanoparticle-based delivery systems and their targeting mechanisms in natural product-based breast cancer therapy and concludes that natural products possess potent anti-breast cancer effects, and the application of nanodelivery technology effectively overcomes their inherent limitations o...
Kai-Yan Su, Yan Li, Dong-Mei Zhang et al.· Pharmaceutics· 0 citations
Abstract Immune checkpoint inhibitors have transformed cancer therapy with the programmed cell death protein 1–programmed death‐ligand 1 axis, demonstrating substantial efficacy by targeting adaptive immunity across multiple malignancies. However, the limited clinical responses observed in a considerable proportion of...
