Open access
Sep 2026
Direct Access to Chiral Piperidines by Enantioselective HAT-Initiated C(sp3)─H Oxidation.
Enantioselective C(sp3)─H functionalization reactions are appealing synthetic organic chemistry tools to streamline access to valuable chiral molecules from simple precursors. Chiral piperidines are ubiquitous motifs in pharmaceuticals and natural products, yet methods for their preparation from simple non-chiral precu...
Sethuraman Muthuramalingam, Josep M. Luis, Arnau Call et al.
· Angewandte Chemie · 0 citations