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Sep 2026

Pd-Catalyzed Asymmetric Tandem Allylic Alkylation/Etherification: Enantioselective Access to Medium-Sized Oxa-spirocycles

Pd-catalyzed asymmetric tandem allylic substitution has proven to be a powerful strategy for constructing chiral rings; however, its application to chiral medium-sized spirocyclic systems remains undeveloped. Herein, we report a Pd-catalyzed asymmetric tandem allylic alkylation/etherification that enables efficient a...

Da-Quan Ai, Qun Li, Yan-Ping Zhang et al. · 1 citation

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