Open access
Aug 2026
Design and in silico evaluation of Thiazole–Isoxazole hybrids as PPARγ-Targeted antidiabetic agents
In this computational study, the thiazole-linked isoxazole compound C139 demonstrated probable antidiabetic activity against PPARγ, but these findings remain predictive and require further validation through comprehensive in vitro and in vivo studies.
Abhirami Pv, Gupta Dheeraj Rajesh, N. V. L. Sirisha Mulukuri et al.
· Frontiers in Bioinformatics · 0 citations