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R. Bahadur

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Open access Sep 2026

Role of ligand-dependent conformational modulation of TNPO3 HEAT-repeat solenoid in nuclear import.

Transportin-3 (TNPO3) is a HEAT-repeat nuclear transport receptor that mediates nuclear import of serine/arginine-rich (SR) proteins and interacts with Ran GTPase during nuclear transport cycle. Although structures of several TNPO3 complexes are available, how ligand binding modulates the conformational landscape of th...

Sonali Chatterjee, Atanu Maity, R. Bahadur · 0 citations
Sep 2026

An atlas of non-redundant sequences and structures of transcription factor assemblies across domains of life.

Transcription factors (TFs) regulate gene expression by controlling the recruitment of transcriptional machinery to regulatory regions of the genome. Nearly 10% of the human genome encodes TFs, making them one of the largest protein families. Despite their central roles in gene regulation, TFs are historically consider...

Swarnava Garai, Shri Kant, R. Bahadur · 0 citations
Open access Sep 2026

HyLnc: a hybrid deep learning and feature-based approach for long non-coding RNA prediction

HyLnc demonstrates that integrating deep contextual representations with biologically interpretable features enhances lncRNA prediction, and provides a robust and scalable solution for large-scale transcriptome annotation and can be extended to other sequence-based prediction.

Amrit Venkatesan, Prashasti Sinha, J. Basak et al. · 1 citation
Open access Jul 2026

Gene regulatory co-expression networks decipher potential lncRNA-miRNA-mRNA interactions modulating transcription regulation in neurodegeneration

A systems-level view of transcriptomic dysregulation across major neurodegenerative diseases is provided and candidate regulatory interactions and molecular targets for future functional investigation are identified.

Amrit Venkatesan, Prashasti Sinha, J. Basak et al. · 0 citations

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