Author

R. Chai

2 papers indexed here

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Review Oct 2026

Proximity Labeling: An Empowering Tool for Deciphering Molecular Mechanisms

Proximity labeling (PL) has become a widely used approach for studying protein–protein interactions (PPIs) and addressing limitations of conventional techniques in capturing transient, weak interactions, and physiological protein networks within living systems. Over the past decade, core PL enzymes, notably APEX2, Bi...

Hao Liang, Shao-Xiang Chen, K.-G. Gan et al. · Journal of Proteome Research · 0 citations

Open access Aug 2026

Rational and computation-assisted engineering of a compact and efficient CRISPR-Cas12f genome editor.

It is demonstrated that integrating protein language model-assisted filtering with structure-guided rational design provides an effective strategy for engineering PspCas12f1 and may facilitate the optimization of additional compact CRISPR nucleases.

Jing-Tong Liu, Sheng-Zhou Wang, Bei Wang et al. · Molecular Therapy · 0 citations