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R. de Cabo

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Open access Aug 2026

Cytotoxic CD4+ T cells induce age-associated myelopoiesis through CCL5-CCR5 signaling.

Age-associated hematopoietic skewing results in an increase in the neutrophil-to-lymphocyte ratio, which serves as a strong predictor of all-cause mortality in older adults, although its causes are incompletely understood. Here we show that cytotoxic CD4+ T lymphocytes accumulate in the bone marrow of mice during aging...

E. Gabandé-Rodríguez, G. Soto-Heredero, Elisa Carrasco et al. · 0 citations
Open access Aug 2026

MSMICA: computational metabolite identification in untargeted metabolomics by integrating MS, retention time, and biological evidence

MSMICA applies multiple pieces of evidence to substantially improve metabolite identification coverage and accuracy for known metabolites and enables greater metabolite identifications, expanded metabolic pathway coverage, and data harmonization.

Jia-Da Zhan, J. Weinberg, William J. Crandall et al. · 0 citations

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