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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

R. Di Santo

h-index 38 View on Semantic Scholar

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Review Open access Aug 2026

Targeting Human Immunodeficiency Virus Integrase Beyond the Active Site: The Discovery and Development of Allosteric Integrase Inhibitors

Given its pivotal role in the viral life cycle, blocking integrase (IN) through IN strand transfer inhibitors (INSTIs) represented a breakthrough in the treatment of HIV infection, establishing these antiretroviral regimens as first‐line options against AIDS. However, the onset of drug‐resistant strains has challenged...

Francesco Saccoliti, E. Patacchini, Emanuele Cara et al. · 0 citations
Open access Aug 2026

Exploring the Pyrimidine Scaffold for the Development of SARS-CoV-2 Mpro Inhibitors.

New SARS-CoV-2 Mpro small-molecule inhibitors endowed with a pyrimidine scaffold are designed and synthesized and the mechanism of action of the most promising compound was elucidated.

Salvatore Nieddu, Giuseppe Ruggieri, Riccardo De Santis et al. · 0 citations

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