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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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R. E. Isaac

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Review Open access Sep 2026

Structure-guided targeting of Plasmodium falciparum aminopeptidase P: exploiting S4' dimer-interface interactions for selective antimalarial drug design.

INTRODUCTION Malaria remains a major global infectious disease, and resistance to frontline antimalarial therapies continues to drive the search for novel drug targets. Plasmodium falciparum aminopeptidase P (PfAPP) is emerging as a promising target because it performs a specialized role in hemoglobin-derived peptide m...

R. E. Isaac, Glenn A. McConkey, Richard Foster et al. · 0 citations

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