Adult-administered chronic nicotine remodels nigral dopaminergic and pedunculopontine cholinergic physiology.
Nicotine is linked to neuroprotection and has been proposed as a potential preventative treatment for Parkinson's disease (PD). Because PD is an aging disorder, such a treatment would necessarily be administered to adults. However, previous studies examining the effects of chronic nicotine in neurons vulnerable to PD h...