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Open access Sep 2026

Blood DNA methylation profile is altered in severe bronchiectasis

Rationale Bronchiectasis is a chronic lung respiratory disease whose systemic aspect is poorly understood. We aimed to characterise the blood DNA methylation profiles of bronchiectasis patients and to determine the relationship of these profiles with disease severity and their functional relevance to circulating immune...

L. Perea, J. Viglino, Belén Solarat et al. · 1 citation
Review Open access Oct 2026

Inflammasomes in respiratory diseases: from disease pathogenesis to drug development and use of multi-omics

Inflammasomes are pivotal for the initiation and control of host inflammatory responses. This is particularly important in the respiratory system due to its direct exposure to noxious environmental and infectious stimuli, which can cause local inflammation, tissue damage and impaired function. Inflammasomes are activat...

R. Shipley, Matthew O'Rourke, Sobia Idrees et al. · 0 citations

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