Sotatercept Improves Right Heart Mechanics Despite Reduced Myocardial Contractility in Pulmonary Arterial Hypertension - A Prospective Exercise Hemodynamic Study
Background: The right ventricular (RV) response to pressure overload is a crucial determinant of outcomes in pulmonary arterial hypertension(PAH). Sotatercept improves clinical outcomes, but its effects on the RV have been inconsistent. We sought to evaluate the effects of sotatercept on load-independent measures of RV...