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R. Fritzen

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Open access Aug 2026

Zinc and metallothionein dysregulation in B cells in multiple sclerosis, with disease-specific CXCR3+/CXCR3⁻ divergence in blood

Introduction Multiple sclerosis (MS) is associated with compartmentalized B-cell responses in the cerebrospinal fluid (CSF), where CXCR3+ B cells contribute to intrathecal immune activity and tissue injury. Zinc is an important regulator of immune-cell function, but zinc homeostasis in pathogenic B-cell populations in...

R. Fritzen · 0 citations

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