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Author

R. Giadone

2 papers indexed here

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Review Oct 2026

Emerging therapies and translational tools for drug development in systemic amyloidosis: insights from the International Society of Amyloidosis Scientific Workshop.

BACKGROUND Amyloidosis is caused by deposition of misfolded proteins as amyloid fibrils in multiple organs. Over the past decade, disease-modifying therapies have markedly improved outcomes in both amyloid light-chain (AL) amyloidosis and amyloid transthyretin (ATTR) amyloidosis. Progress in AL amyloidosis has been dri...

Gareth J. Morgan, A. Dispenzieri, Jing Fu et al. · 0 citations
Open access Oct 2026

Disease-associated mutations directionally modulate epigenetic age in iPSC-derived tissues

Reprogramming somatic cells into induced pluripotent stem cells (iPSCs) resets epigenetic age, creating a major challenge for modeling age-associated cellular states and limiting the use of iPSCs in aging research beyond the genetic component. Recent work has shown that healthy organoids can re-accumulate age-associate...

Nicholas J. Skvir, Todd W. Dowrey, Samuel F. Cranston et al. · 0 citations

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