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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

R. Giniatullin

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2 papers indexed here

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Open access 2026

Electrophysiological analysis of purinergic signaling of microglia as an approach to studying the immune mechanisms of Alzheimer's disease

Neuroinflammation mediated by chronic microglial activation is considered a key factor in the pathogenesis of Alzheimer's disease (AD). Purinergic signaling, particularly P2X4 and P2X7 receptors activated by extracellular ATP, plays an important role in modulating microglial function. Understanding the ionic mechanisms...

G. T. Tasibekova, N. Novosolova, M. K. Zholdasova et al. · 0 citations
Open access Aug 2026

Mechanical Activation of Piezo1 by Virus-like Nanospikes to Potentiate STING-driven Macrophage Reprogramming

Mechanotransduction plays a fundamental role in regulating immune cell function, yet how engineered virus-like nanospikes engage mechanosensitive signaling pathways to modulate innate immunity remains poorly understood. Here, we report virus-like nanotopography as a previously unrecognized regulator of Piezo1-mediated...

Jiajia Wang, Minna Sivonen, E. Batnasan et al. · 0 citations

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