Introduction Hemin, an oxidized heme species released during erythrocyte breakdown, is detectable in gingival crevicular fluid during periodontal inflammation, but its effects on local immune signaling remain unclear. We investigated whether hemin modifies cytokine-induced interferon responses in HSC-2 oral squamous ce...
Xiao-Yu Huang, R. Gruber, Layla Panahipour· Frontiers in Immunology· 0 citations
Background/Objectives: Dental procedure-related emphysema is an infrequently reported complication of dental care that may extend from superficial facial tissues into deep cervical, mediastinal, orbital, thoracic, intracranial, or vascular compartments. This revised scoping review aimed to map contemporary published ca...
U. Kuchler, Laura Scholter, R. Gruber· Dental journal· 0 citations
Exosomes have emerged as promising cell-free therapeutic agents for tissue regeneration. However, chronic inflammation, a hallmark of periodontal disease, may impair their osteogenic potential. This systematic review evaluated how inflammatory conditions influence the ability of exosomes to modulate osteogenesis in hum...
Alan Alves Machado, Lara Steiner Back, Gilberto de Souza Melo et al.· Odontology : official journa...· 0 citations
Findings identify a previously unrecognized host-modulatory activity of a zinc-containing Listerine® formulation characterized by selective attenuation of interferon-associated inflammatory transcription together with induction of a zinc-responsive metallothionein program.
Xiao-Yu Huang, Anna Podesser, M. Cengiz et al.· Frontiers in Immunology· 1 citation· ⚡1
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