The COVID-19 pandemic substantially disrupted tuberculosis (TB) prevention, diagnosis, and treatment services worldwide. Despite increased TB notifications in Nepal during the post-pandemic recovery period, the geographic distribution and temporal clustering of notifications remain poorly understood. This study examine...
N. Bisht, R. Bhatt, P. Rijal et al.· medRxiv· 0 citations
Background Translation of tuberculosis (TB) biomarker and diagnostic research into tools that improve patient and public health outcomes has been slow, partly because no internationally agreed framework exists defining the use cases that new biomarkers and tests should address. We aimed to identify, validate, and prior...
S. Wright, F. Fama, A. de Wilton et al.· medRxiv· 0 citations
Sotrovimab pre-exposure prophylaxis in an immunocompromised patient did not prevent SARS-CoV-2 infection, and was selected for resistant mutation E340D, with unexpected fitness consequences across non-receptor binding domain spike regions.
K. Kamelian, D. Pascall, Mei-Jun Cheng et al.· medRxiv· 1 citation
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