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Open access Aug 2026

Active site engineering of recombinant human paraoxonase 1 for enhancing its catalytic efficiency against V-type nerve agent analog- Demeton S

Human Paraoxonase 1 (HuPON1) is a calcium-dependent serum enzyme with broad substrate specificity and therapeutic potential for detoxifying the organophosphates, including nerve agents. The V-type nerve agents are the most toxic synthetic organophosphates, with high lethality and environmental persistence, necessitatin...

Manik Goel, Pulkita Pandey, Subhashree Sahu et al. · 0 citations

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