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Open access Sep 2026

Redox control and mechanisms of transmembrane signaling in CSS domain c-di-GMP phosphodiesterases that control biofilm formation in Escherichia coli

ABSTRACT Bis-(3′,5′)-cyclic dimeric guanosine monophosphate (c-di-GMP) control of biofilm formation in Escherichia coli K-12 is balanced by multiple diguanylate cyclases (DGCs) and c-di-GMP-specific phosphodiesterases (PDEs). Five of the 13 PDEs feature a periplasmic CSS domain with two conserved cysteines, flanked by...

Katharina Pressler, Martin Lorkowski, R. Hengge · 0 citations

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