R. Henrique

CDHR5 and UPB1 expression associated with promoter methylation in sarcomatoid differentiated clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) represents the most frequent histological subtype of renal cell carcinoma (RCC). Sarcomatoid (de)differentiation is associated with metastatic dissemination and dismal prognosis. Altered DNA methylation occurs during ccRCC progression but a specific role in the emergence of sarco...

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

High‐risk non‐muscle invasive bladder cancer (NMIBC) is a common urological malignancy with a high propensity for recurrence (30–40% of patients) despite treatment with Bacillus Calmette–Guérin (BCG) instillations. Identifying patients who are likely to respond or not to BCG therapy before treatment initiation may sign...

Influence of RNA Modifications on Cancer Metabolism: Interplay with Hypoxia and Therapeutic Implications.