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Author

R. Horton

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2 papers indexed here

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Review Sep 2026

Left Atrial Appendage Closure: Past, Present, and Future

Left atrial appendage closure (LAAC) has emerged as an important alternative strategy for stroke prevention in patients with non-valvular atrial fibrillation (NVAF), particularly when long-term oral anticoagulation (OAC) is contraindicated or poorly tolerated. Initially developed as a surgical technique based on ligati...

E. Zito, Pamela Horton Embrey, V. L. La Fazia et al. · 0 citations
Jul 2026

Effect of Left Atrial Size and Volume Reduction on Pulmonary Vein Isolation Efficacy in Patients With Persistent and Longstanding Persistent Atrial Fibrillation: Subset Analysis From the aMAZE Trial.

The correlation of LAV with PVI effectiveness in this study demonstrates that AA recurrence after PVI alone is directly related to increasing LAV, and left atrial appendage ligation may provide an adjunctive benefit in patients with nonparoxysmal AF and enlarged LAV.

Dhanunjaya R. Lakkireddy, David J. Wilber, Suneet Mittal et al. · 0 citations

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