Importance: Upper extremity impairment is a leading cause of post-stroke disability, yet clinically approved neuromodulation therapies are currently limited by the risks and costs of surgical implantation. There is an unmet need for non-invasive brain stimulation. Objective: To evaluate the feasibility, safety, and pre...
C. Merrick, F. Dai, S. Singh et al.· medRxiv· 0 citations
Cerebellar ataxia results in debilitating impairments in balance, gait, and cognition, with no established effective treatments. Kilohertz transcranial magnetic perturbation (kTMP) is a novel subthreshold non-invasive brain stimulation (NIBS) method that delivers strong, subthreshold electric fields to the cerebellar c...
Amanda Chirino-Pérez, C. Merrick, Fredy Miranda-Casasola et al.· Cerebellum· 0 citations
Multiple learning processes contribute to successful goal-directed actions under changing physiological states, biomechanical constraints, and environmental contexts. Among these, explicit strategies enable us to discover new movement patterns when existing ones no longer achieve the desired outcome. Yet, how strategie...
Anjuli Niyogi, Elizabeth Cisneros, Wei Ding et al.· bioRxiv· 0 citations
Together they suggest that thalamic dynamics contribute to motor learning through multiple mechanisms: beta-band power reflects the emergence of learned motor representations, whereas beta–high-frequency coupling is enhanced when the context is less predictable.
Angela Voegtle, L. Buentjen, Stefan Repplinger et al.· bioRxiv· 0 citations
Kilohertz transcranial magnetic perturbation achieves cortical E-fields an order of magnitude higher than conventional subthreshold tES while maintaining robust safety margins and tolerability indistinguishable from sham, supporting its use for rigorous double-blind studies and translational settings.
C. Merrick, Guy Avraham, P. Reber et al.· Journal of Neural Engineerin...· 1 citation
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