Tuberculosis remains a major infectious disease, and the increasing incidence of multidrug‐resistant Mycobacterium tuberculosis continues to limit current treatment options. This review summarizes recent medicinal chemistry efforts directed toward six important M. tuberculosis targets: InhA, DprE1, MmpL3, QcrB, DNA gyr...
R. Kalita, K. Kolekar, Sachin Kumar Singh et al.· Archiv der Pharmazie· 0 citations
INTRODUCTION
The urgent need for novel antimicrobials to combat antibiotic resistance highlights benzimidazole derivatives as highly promising candidates. Over the past decade, extensive research has focused on the therapeutic potential of benzimidazole-based scaffolds in various pathological conditions, including bact...
R. Kalita, Shivani Sharma, Mukta Gupta· Mini-Reviews in Medical Chem...· 0 citations
The recent patents, especially on MDM2 inhibitors and other anticancer agents with nanomolar potency, provide further evidence for the continued interest in spirooxindole‐based drug discovery.
R. Kalita, Sarbanga Bezbaruah, D. Patle· ChemMedChem· 0 citations
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