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R. L. Gurung

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Open access Sep 2026

Pathway‐Specific Polygenic Risk Score and Risk of Hyperglycaemic Progression in Patients With Type 2 Diabetes

Pathway‐specific polygenic risk scores (psPRS) provide insights into the heterogeneity of type 2 diabetes. We aim to study whether psPRS for beta cell dysfunction, obesity and metabolic syndrome associate with risk of hyperglycaemic progression in Southeast Asian patients with type 2 diabetes.

Sylvia Liu, Hui-Li Zheng, Jia Le Ivan Tan et al. · 0 citations
Open access Aug 2026

Genome-wide DNA methylation analysis revealed epigenetic mechanism underlying end-stage renal disease

A large-scale two-stage epigenome-wide association study of ESRD in two independent cohorts identifies 52 ESRD-associated differentially methylated CpG positions (ESRD DMPs) showing consistent association between the two cohorts and across diverse kidney diseases, implicating 144 candidate genes enriched in inflammator...

Xiao-Hong Zhou, Dianchun Shi, Jin-Jin Xu et al. · 0 citations

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