Abstract Introduction Interleukin-22 (IL-22), a member of the IL-10 cytokine family, primarily targets non-haematopoietic epithelial and stromal cells, contributing to maintenance of epithelial barrier integrity, antimicrobial immunity and tissue regeneration. In this study, we sought to evaluate the association betwee...
I. Ferraz-Amaro, J. C. Quevedo-Abeledo, B. Tejera-Segura et al.· Lupus Science and Medicine· 0 citations
Background Interleukin-5 (IL-5) is the principal regulator of eosinophil biology and a key mediator of type 2 immune responses. Despite its recognized role in autoimmunity, its contribution to the pathophysiology of systemic lupus erythematosus (SLE) remains poorly defined, and no previous study has quantified IL-5 usi...
I. Ferraz-Amaro, J. C. Quevedo-Abeledo, B. Tejera-Segura et al.· Journal of Translational Aut...· 0 citations
KDELR2
encodes a cis-Golgi membrane receptor that functions recycling endoplasmic reticulum (ER) proteins bearing a C-terminal KDEL-like sequence. Pathogenic variants in this gene have previously been associated with osteogenesis imperfecta (OI). Herein, we studied the phenotype of
Kdelr2
-knockout mice both at...
J. A. Jiménez-Estrada, Carmen-Lisset Flores, Almudena Fernández et al.· Scientific Reports· 0 citations
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