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Author

R. Malkawi

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Open access Oct 2026

Vitamin D status and inflammatory Interleukins in women with and without polyendocrine metabolic ovarian syndrome: a cross-sectional exploratory study

Abstract Background Polyendocrine Metabolic Ovarian Syndrome (PMOS), formerly referred to as polycystic ovary syndrome (PCOS), is an intricate endocrine disorder, defined by a constellation of hormonal, metabolic, and reproductive irregularities. Vitamin D deficiency and increased levels of interleukin-6 (IL-6) and int...

Roba Bdeir, Nour A. Al-Sawalha, H. Rawashdeh et al. · 0 citations
Open access Sep 2026

Design and Preparation of Solid Lipid Nanoparticles to Enhance Physicochemical Properties of Etoricoxib

Objective: Etoricoxib is a selective COX-2 inhibitor with poor aqueous solubility, which may limit its dissolution behavior and physicochemical performance. This study aimed to design, prepare, and optimize etoricoxib-loaded solid lipid nanoparticles (SLNs) to enhance the physicochemical properties and in vitro release...

Ahmed R. Gardouh, R. Malkawi, Ahmed Raja Alanezi · 0 citations
Open access Jul 2026

FORMULATION AND PHYSICOCHEMICAL CHARACTERIZATION OF PACLITAXEL-LOADED PLGA NANOPARTICLES WITH ENHANCED SOLUBILITY AND IN VITRO ANTICANCER ACTIVITY

Objective: Paclitaxel is a widely used chemotherapeutic agent with extremely poor aqueous solubility (~0.3 µg/ml), which significantly limits its bioavailability and therapeutic efficacy. The present study aimed to develop and characterize paclitaxel-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles to enhance...

R. Malkawi · 0 citations

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