Open access
Oct 2026
A CXCR4-Targeted Dual-Acting Nanoconjugate Combines Protein-Toxin and Small-Molecule Warheads for Synergistic Cytotoxicity
Self-assembling multivalent protein nanoparticles with an architecture based on His-metal coordination and specific binding to cancer stem cells have emerged as promising tools for the selective delivery of microbial toxins in oncology, reaching precise cytotoxic effects. The incorporation of small-molecule drugs aim...
Julián I. Mendoza, Ariana Rueda, Gemma Quijada et al.
· Bioconjugate chemistry · 0 citations