In vitro antiviral effects of an mTORC1 inhibitor targeting the rapamycin-binding protein complex.
The persistent threat of mutable viral pathogens highlights the need for broad-spectrum antiviral drugs that target stable host factors to provide a high genetic barrier to resistance. The mammalian target of rapamycin complex 1 (mTORC1) serves as a central metabolic bottleneck in cellular metabolism. It is commonly co...