Modulatory effects of S1QEL on OxLDL-induced metabolic alterations and inflammatory responses in human monocytes
Background Oxidized low-density lipoprotein (OxLDL) plays a key role in initiating monocyte activation, glycolytic reprogramming, and pro-inflammatory cytokine production—processes that contribute to aging and progression of age-related diseases such as atherosclerosis and steatohepatitis. Mitochondrial reactive oxygen...