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Author

R. Mirmira

2 papers indexed here

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Review Open access Sep 2026

Development and validation of a model using routine clinical features to improve diabetes diagnosis

Abstract Context Hemoglobin A1c (A1c) and fasting plasma glucose (FPG) miss diabetes diagnosis in many individuals, but the alternative, oral glucose tolerance testing (OGTT), is difficult to obtain. Objective This work aimed to develop and validate a model to identify diabetes missed by A1c and FPG but detected by OGT...

A. Hutchison, Simar Narula, B. Faubert et al. · 0 citations
Open access Sep 2026

A Novel PD-L1 Splice Isoform Modulates β Cell Communication in Response to Interferon Signaling

β cell expression of the immune checkpoint ligand PD-L1 (encoded by CD274) limits autoimmune β cell destruction in type 1 diabetes (T1D). β cell display PD-L1 not only at the cell surface but also secreted on extracellular vesicles (EVs), which bind PD-1 and restrain CD8+ T cell activation. β cell IFN signaling is an e...

Chaitra Rao, Fei Huang, Saptarshi Roy et al. · 0 citations

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