Rational design strategies for rhodanine-based heterocycles and their therapeutic potential as antibacterial, anti-diabetes, anti-Alzheimer’s, anticancer, anthelmintic, anti-obesity, and against COVID-19 are discussed.
R. Nath, Lakshminarayan Das, Arka Chakraborty et al.· Phosphorus Sulfur and Silico...· 0 citations
This review covers advances in designing and synthesizing bioactive heterocycles, highlighting structure-based drug design (SBDD) and ligand-based drug design (LBDD) approaches with computational modeling and Artificial Intelligence (AI) to find potent, selective molecules with good Absorption, Distribution, Metabolism...
Debajit Dewan, Bhupender Nehra, R. Nath et al.· Future Medicinal Chemistry· 0 citations
A contemporary assessment of biological macromolecule research is provided, highlighting how technological advancements continue to fill the existing bridge and integrate the prior understanding of complex biomolecular systems while addressing persistent technical challenges in their characterization, with finesse.
Rabab Fatima, Bhupender Nehra, Biplab Debnath et al.· Critical reviews in analytic...· 0 citations
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